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Agomelatine in the treatment of seasonal affective disorder
WebSecondary endpoints included assessment of clinical response (defined as a reduction in total MADRS score of ≥50%), and change in Clinical Global Impression scales, Global Assessment of Functioning scale, Sheehan Disability Scale, and CircScreen sleep questionnaire scores. Safety and tolerability were also monitored. WebAntidepressant effectiveness was evaluated by Beck Depression Inventory (BDI-II), effects on daytime activity by two questions of Circscreen (patient questionnaire), compliance by standardized questions. ADRs were documented every visit.Included patients (BDI-II total score 31.9) improved during 6 months treatment with agomelatine (BDI-II 9.6). cypraea hesitata
(PDF) Agomelatine as monotherapy for major depression
WebThe antidepressant efficacy of agomelatine in daily practice: Results of the non-interventional study VIVALDI - Volume 26 Issue S2 WebJan 1, 2011 · Agomelatine is a melatonergic agonist and 5-HT 2C antagonist with demonstrated antidepressant efficacy in clinical trials. The aim of the non-interventional study VIVALDI was to examine the antidepressant efficacy and tolerability of agomelatine in depressed patients in daily practice. Methods WebAug 3, 2016 · 环状RNA(circRNA)是动物细胞中广泛存在的一种非编码RNA形式,分子呈封闭环状结构,不受RNA外切酶的影响,表达稳定,不易降解。 已有的研究表 … cypraea hirasei