WitrynaHowever, mild hyperthermia (42 °C) rapidly destabilized the ZBTB16/RARα fusion protein expressed in HeLa, 293T, and OCI-AML3 cells, followed by robust ubiquitination and proteasomal degradation. In contrast, hyperthermia did not affect the normal (i.e., unfused) ZBTB16 and RARα proteins, suggesting a specific thermal sensitivity of the ... Witryna1 lip 2024 · As hyperthermia and ATO destabilized P/R through different mechanisms, combination of hyperthermia with ATO might have synergistic effects. An elevated …
Temperature management in critically ill patients BJA …
WitrynaHyperthermia Selectively Destabilizes Oncogenic Fusion Proteins Yasen Maimaitiyiming 1,2,3 , Qian Qian Wang 1,3 , Chang Yang 1,3 , Yasumitsu Ogra 4 , Yinjun Lou 5 , Witryna7 kwi 2024 · Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells. Francesco Maura; … literally you
International Journal of Hyperthermia: Vol 40, No 1 (Current issue)
WitrynaIn short, these results demonstrate that hyperthermia could effectively destabilize and subsequently degrade the ZBTB16/RARα fusion protein in an NCoR-dependent … Witryna11 maj 2024 · Recently, a research team led by Prof. Hua Naranmandura and Prof. Chih-Hung Hsu from the Zhejiang University School of Medicine for the first-time revealed that Hyperthermia could destabilize... Witryna4 kwi 2024 · A variety of studies indicated that inorganic arsenic and its methylated metabolites have paradoxical effects, namely, carcinogenic and anticancer effects. Epidemiological studies have shown that long term exposure to arsenic can increase the risk of cancers of lung, skin or bladder in man, which is probably associated with the … importance of inclusivity in the workplace