WebOptic nerve hypoplasia is always present in septo-optic dysplasia. The optic nerve head is often gray or pale and typically one-third to one-half normal size. Classically, the optic … WebCPHD is a disorder characterized by impaired production of two or more anterior and/or posterior pituitary hormones. CPHD clinical features may include short stature, hypothyroidism, impaired sexual maturation, and hypo-cortisolism, either individually or simultaneously [ 2 ].
Optic Nerve Hypoplasia Children’s Hospital Los Angeles
WebSepto-optic dysplasia (SOD), known also as de Morsier syndrome, is a rare congenital malformation syndrome that features a combination of the underdevelopment of the optic nerve, pituitary gland dysfunction, and absence of the septum pellucidum (a midline part of the brain). Two or more of these features need to be present for a clinical diagnosis — … WebMar 28, 2024 · In the majority of patients, optic nerve hypoplasia will be bilateral, but the degree of dysplasia of the optic nerve is often asymmetric [ 6 ]. Endocrinologic deficits have been reported in 58–78% of children with septo-optic dysplasia [ 2, 8, 9 ], and the most common abnormality is growth hormone deficiency [ 8, 10, 11 ]. novartis consumer health gmbh
Pituitary Hypoplasia and Other Midline Developmental Anomalies
WebSepto-optic dysplasia is a disorder of early brain and eye development. The most common features are underdevelopment (hypoplasia) of the eye (optic) nerve, abnormal formation of structures along the midline of the brain such as the absence of the septum pellucidum and the corpus callosum, and a small pituitary (pituitary hypoplasia). WebNov 15, 2011 · Presenting features and long-term effects of growth hormone treatment of children with optic nerve hypoplasia/septo-optic dysplasia Presenting features and long … WebJul 22, 2009 · Introduction. The diagnosis of septo-optic dysplasia (SOD) is a clinical one and can be made when two or more features of the classical triad of (i) optic nerve … novartis consumer health münchen